Pipeline

The current pipeline of OncoBone Therapeutics includes five therapeutic assets for oncology indications involving bone metastases, such as Castration-Resistant Prostate Cancer (CRPC), Triple-Negative Breast Cancer (TNBC) and Multiple Myeloma (MM). In addition, several potential assets are under evaluation.

Click the to find out more about the therapeutic asset of each partner

Indication
Therapeutic asset
Discovery In vitro In vivo-efficacy In vivo-safety Clinical Trials Regulatory approval
Bone metastasizing malignancies
OBP- 001 Humanised antibody
On hold due to funding/licensing negotiations

OBP-001 is a first-in-class humanized immunomodulating antibody being developed for bone metastasizing malignancies. Currently on hold due to funding/licensing negotiations that are estimated to be completed in early 2026.

Bone metastasizing malignancies
OBP- 002 Small molecule inhibitor
Out-licensing for clinical development estimated in 2029

OBP-002 is a first-in-class small-molecule inhibitor being developed for bone metastasizing malignancies. The asset is currently in lead optimization phase.

Bone predominant TNBC
OTX- 001 Small molecule inhibitor
Out-licensing for clinical development estimated in 2027

OTX-001 is a first-in-class small-molecule inhibitor being developed for TNBC and other bone metastasizing malignancies. Proof-of-concept studies are to be completed, followed by regulatory safety and other IND-enabling studies, and out-licensing for clinical development.

Multiple myeloma
OTX- 002 Antibody-drug conjugate
Out-licensing for clinical development estimated in 2028

OTX-002 is a first-in-class ADC being developed for MM. Proof-of-concept studies are to be completed, followed by regulatory safety and other IND-enabling studies, and out-licensing for clinical development.

Bone metastatic CRPC
OTX- 003 Radio-pharmaceutical
Out-licensing for clinical development estimated in 2028

OTX-003 is a first-in-class radiopharmaceutical being developed for CRPC and other bone metastasizing malignancies. Proof-of-concept studies are to be completed, followed by regulatory safety and other IND-enabling studies, and out-licensing for clinical development.

Oncobone Col
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